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CD10 Rabbit Polyclonal Antibody (CD10)

CD10 Rabbit Polyclonal Antibody (CD10)

CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.

Catalog No: FY-IG0159
Regular price $239.00 USD
Regular price Sale price $239.00 USD
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Packaging
1.5 weeks

Product Details

Application(s) IHC
Species Reactivity Human, Mouse, Rat
Source Rabbit
Ab Type Polyclonal
Isotype IgG
Immunogen Recombinant Protein
Dilution IHC 1:200-500
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. Store at -20C. Avoid repeated freeze-thaw cycles. Stable for one year from the date of shipment.
Regulatory Status For Research Use Only
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