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Human ABCG8 (Atp-binding Cassette Sub-family G Member 8) ELISA Kit
Human ABCG8 (Atp-binding Cassette Sub-family G Member 8) ELISA Kit
The Human (ABCG8) Atp-binding Cassette Sub-family G Member 8 ELISA Kit measures Atp-Binding Cassette Sub-Family G Member 8 in samples. The plate has been pre-coated with Human ABCG8 antibody. ABCG8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ABCG8 Antibody is added and binds to ABCG8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ABCG8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ABCG8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6711Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
12.63 ng/L
Detection Range
20-7000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cardiovascular
Background
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: 15054092). The heterodimer with ABCG5 has ATPase activity (PubMed: 16893193, PubMed: 20210363, PubMed: 27144356). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Atp-Binding Cassette Sub-Family G Member 8
Regulatory Status
For Research Use Only
