1
/
of
1
Human Angiopoietin-1 Receptor (TEK) ELISA Kit
Human Angiopoietin-1 Receptor (TEK) ELISA Kit
This ELISA kit is designed to detect Human Angiopoietin-1 Receptor (Human TEK). The assay plate has been pre-coated with mouse anti-Human TIE2 monoclonal antibody. When the sample containing TIE2 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human TIE2 Antibody is added to the wells and binds to TIE2 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human TIE2 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE123
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
21.95 pg/mL
Detection Range
78.125-5000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Neuroscience, Cardiovascular, Developmental biology, Signal Transduction, Stem cells, Cancer
Background
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Angiopoietin-1 receptor
Regulatory Status
For Research Use Only
