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Human ANTXR2 (Anthrax Toxin Receptor 2) ELISA Kit
Human ANTXR2 (Anthrax Toxin Receptor 2) ELISA Kit
The Human (ANTXR2) Anthrax Toxin Receptor 2 ELISA Kit measures Anthrax Toxin Receptor 2 in samples. The plate has been pre-coated with Human ANTXR2 antibody. ANTXR2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ANTXR2 Antibody is added and binds to ANTXR2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ANTXR2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ANTXR2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2398Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.26 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Necessary for cellular interactions with laminin and the extracellular matrix.
(Microbial infection) Receptor for the protective antigen (PA) of B.anthracis (PubMed:12700348, PubMed:15243628, PubMed:15326297).
Binding of PA leads to heptamerization of the receptor-PA complex (PubMed:12700348, PubMed:15243628, PubMed:15326297).
Upon binding of the PA of B.anthracis, the complex moves to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway (PubMed:12551953, PubMed:15337774).
In the endosomal membrane, at pH under 7, the complex then rearranges and forms a pore allowing the other components of anthrax toxin to escape to the cytoplasm (PubMed:12551953, PubMed:15337774). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Anthrax Toxin Receptor 2
Regulatory Status
For Research Use Only
