1
/
of
1
Human ANXA1 (Annexin A1) ELISA Kit
Human ANXA1 (Annexin A1) ELISA Kit
The Human (ANXA1) Annexin A1 ELISA Kit measures Annexin A1 in samples. The plate has been pre-coated with Human ANXA1 antibody. ANXA1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ANXA1 Antibody is added and binds to ANXA1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ANXA1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ANXA1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3288Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
0.18 ng/mL
Detection Range
0.3-90 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed: 8425544). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (By similarity). Promotes resolution of inflammation and wound healing (PubMed: 25664854). Functions at least in part by activating the formyl Peptide receptors and downstream signaling cascades (PubMed: 15187149, PubMed: 25664854). Promotes chemotaxis of granulocytes and monocytes via activation of the formyl Peptide receptors (PubMed: 15187149). Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed: 17008549). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PubMed: 17008549). Has no effect on unstimulated T cells (PubMed: 17008549). Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration (PubMed: 15187149). Negatively regulates hormone exocytosis via activation of the formyl Peptide receptors and reorganization of the actin cytoskeleton (PubMed: 19625660). Has high affinity for Ca(2+) and can bind up to eight Ca(2+) ions (By similarity). Displays Ca(2+)-dependent binding to phospholipid membranes (PubMed: 2532504, PubMed: 8557678). Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca(2+)-dependent interaction between phagosomes and the actin cytoskeleton (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Annexin A1
Regulatory Status
For Research Use Only
