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Human Apolipoprotein A-I (APOA1) ELISA Kit
Human Apolipoprotein A-I (APOA1) ELISA Kit
This ELISA kit is designed to detect Human Apolipoprotein A-I (Human APOA1). The assay plate has been pre-coated with mouse anti-Human Apolipoprotein A-I monoclonal antibody. When the sample containing Apolipoprotein A-I is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human Apolipoprotein A-I Antibody is added to the wells and binds to Apolipoprotein A-I in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human Apolipoprotein A-I present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE117
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
58.55 pg/mL
Detection Range
250-8000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Background
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Apolipoprotein A-I
Regulatory Status
For Research Use Only
