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Human ARF6 (Adp-Ribosylation Factor 6) ELISA Kit
Human ARF6 (Adp-Ribosylation Factor 6) ELISA Kit
The Human (ARF6) Adp-Ribosylation Factor 6 ELISA Kit measures Adp-Ribosylation Factor 6 in samples. The plate has been pre-coated with Human ARF6 antibody. ARF6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ARF6 Antibody is added and binds to ARF6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ARF6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ARF6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4599Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
1.59 ng/L
Detection Range
3-900 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed: 11266366, PubMed: 21170023, PubMed: 16737952, PubMed: 7589240, PubMed: 18400762). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (PubMed: 14978216). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1 (By similarity). Required for NTRK1 sorting to the recycling pathway from early endosomes (By similarity). (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Adp-Ribosylation Factor 6
Regulatory Status
For Research Use Only
