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Human Platelet-Derived Growth Factor Receptor Beta (PDGFRB) ELISA Kit
Human Platelet-Derived Growth Factor Receptor Beta (PDGFRB) ELISA Kit
This ELISA kit is designed to detect Human Platelet-Derived Growth Factor Receptor Beta (Human PDGFRB). The assay plate has been pre-coated with mouse anti-Human PDGFRB monoclonal antibody. When the sample containing PDGFRB is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human PDGFRB Antibody is added to the wells and binds to PDGFRB in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human PDGFRB present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE101
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
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per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
13.08 pg/mL
Detection Range
62.5-4000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cancer, Signal Transduction, Cardiovascular, Microbiology, Neuroscience
Background
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Platelet-derived growth factor receptor beta
Regulatory Status
For Research Use Only
