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Human Platelet Endothelial Cell Adhesion Molecule (PECAM1) ELISA Kit
Human Platelet Endothelial Cell Adhesion Molecule (PECAM1) ELISA Kit
This ELISA kit is designed to detect Human Platelet Endothelial Cell Adhesion Molecule (Human PECAM1). The assay plate has been pre-coated with mouse anti-Human CD31 monoclonal antibody. When the sample containing CD31 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human CD31 Antibody is added to the wells and binds to CD31 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human CD31 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE030
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
8.15 pg/mL
Detection Range
18.75-12000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology, Cancer, Cardiovascular, Signal Transduction, Stem cells
Background
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Platelet endothelial cell adhesion molecule
Regulatory Status
For Research Use Only
