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Human ABCA3 (Atp-binding Cassette Sub-family A Member 3) ELISA Kit
Human ABCA3 (Atp-binding Cassette Sub-family A Member 3) ELISA Kit
The Human (ABCA3) Atp-binding Cassette Sub-family A Member 3 ELISA Kit measures Atp-Binding Cassette Sub-Family A Member 3 in samples. The plate has been pre-coated with Human ABCA3 antibody. ABCA3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ABCA3 Antibody is added and binds to ABCA3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ABCA3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ABCA3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3037Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
10.03 ng/L
Detection Range
20-3800 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Catalyzes the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant (PubMed: 16959783, PubMed: 17574245, PubMed: 28887056, PubMed: 31473345, PubMed: 27177387). Transports preferentially phosphatidylcholine containing short acyl chains (PubMed: 27177387). In addition plays a role as an efflux transporter of miltefosine across macrophage membranes and free cholesterol (FC) through intralumenal vesicles by removing FC from the cell as a component of surfactant and protects cells from free cholesterol toxicity (PubMed: 26903515, PubMed: 25817392, PubMed: 27177387). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Atp-Binding Cassette Sub-Family A Member 3
Regulatory Status
For Research Use Only
