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Human ADCY6 (Adenylate Cyclase Type 6) ELISA Kit
Human ADCY6 (Adenylate Cyclase Type 6) ELISA Kit
The Human (ADCY6) Adenylate Cyclase Type 6 ELISA Kit measures Adenylate Cyclase Type 6 in samples. The plate has been pre-coated with Human ADCY6 antibody. ADCY6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ADCY6 Antibody is added and binds to ADCY6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ADCY6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ADCY6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2158Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.025 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed: 17916776, PubMed: 17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed: 17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function (By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed: 17916776). Contributes to bone cell responses to mechanical stimuli (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Adenylate Cyclase Type 6
Regulatory Status
For Research Use Only
