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Human ADRBK1 (Beta-Adrenergic Receptor Kinase 1) ELISA Kit
Human ADRBK1 (Beta-Adrenergic Receptor Kinase 1) ELISA Kit
The Human (ADRBK1) Beta-Adrenergic Receptor Kinase 1 ELISA Kit measures Beta-Adrenergic Receptor Kinase 1 in samples.
Catalog No:
E6544Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
4.95 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Enzyme & Kinase
Background
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PubMed: 19715378). Key regulator of LPAR1 signaling (PubMed: 19306925). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PubMed: 19306925). Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed: 19306925). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity). Inhibits relaxation of airway smooth muscle in response to blue light (PubMed: 30284927). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Beta-Adrenergic Receptor Kinase 1
Regulatory Status
For Research Use Only
