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Human Beta-Nerve Growth Factor (NGF) ELISA Kit
Human Beta-Nerve Growth Factor (NGF) ELISA Kit
This ELISA kit is designed to detect Human Beta-Nerve Growth Factor (Human NGF). The assay plate has been pre-coated with mouse anti-Human NGF monoclonal antibody. When the sample containing NGF is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human NGF Antibody is added to the wells and binds to NGF in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human NGF present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE167
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.92 pg/mL
Detection Range
2.19-140 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Neuroscience
Background
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Beta-nerve growth factor
Regulatory Status
For Research Use Only
