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Human C-C Motif Chemokine 14 (CCL14) ELISA Kit
Human C-C Motif Chemokine 14 (CCL14) ELISA Kit
This ELISA kit is designed to detect Human C-C Motif Chemokine 14 (Human CCL14). The assay plate has been pre-coated with mouse anti-Human CCL14 monoclonal antibody. When the sample containing CCL14 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human CCL14 Antibody is added to the wells and binds to CCL14 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human CCL14 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE092
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
4.16 pg/mL
Detection Range
18.75-1200 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology, Metabolism, Signal Transduction
Background
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
C-C motif chemokine 14
Regulatory Status
For Research Use Only
