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Human C-C Motif Chemokine 16 (CCL16) ELISA Kit

Human C-C Motif Chemokine 16 (CCL16) ELISA Kit

This ELISA kit is designed to detect Human C-C Motif Chemokine 16 (Human CCL16). The assay plate has been pre-coated with mouse anti-Human LEC monoclonal antibody. When the sample containing LEC is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human LEC Antibody is added to the wells and binds to LEC in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human LEC present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.

Catalog No: BPE094
Regular price $624.00 USD
Regular price $480.00 USD Sale price $624.00 USD
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Product Details

Species Reactivity Human
Sensitivity 0.54 pg/mL
Detection Range 2.34-150 pg/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 3.5 hour(s)
Research Areas Immunology, Cardiovascular
Background CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was transfected with human CCL16 cDNA and, in comparison with other cytokines, was shown to be the faster inducer of systemic immune response due to massive, prompt infiltration of leukocytes. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life This product can be stored at 2-8C.
Analyte C-C motif chemokine 16
Regulatory Status For Research Use Only
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