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Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) ELISA Kit
Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6) ELISA Kit
This ELISA kit is designed to detect Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Human CEACAM6). The assay plate has been pre-coated with mouse anti-Human CEACAM6 monoclonal antibody. When the sample containing CEACAM6 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human CEACAM6 Antibody is added to the wells and binds to CEACAM6 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human CEACAM6 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE137
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
4.74 pg/mL
Detection Range
15.6-1000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Tags and Cell Markers
Background
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Carcinoembryonic antigen-related cell adhesion molecule 6
Regulatory Status
For Research Use Only
