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Human CBX2 (Chromobox Protein Homolog 2) ELISA Kit
Human CBX2 (Chromobox Protein Homolog 2) ELISA Kit
The Human (CBX2) Chromobox Protein Homolog 2 ELISA Kit measures Chromobox Protein Homolog 2 in samples. The plate has been pre-coated with Human CBX2 antibody. CBX2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human CBX2 Antibody is added and binds to CBX2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CBX2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human CBX2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2894Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
3.71 ng/L
Detection Range
7-1500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed: 21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed: 21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, acting as activator of NR5A1 expression (PubMed: 19361780). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Chromobox Protein Homolog 2
Regulatory Status
For Research Use Only
