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Human Dickkopf-Related Protein 3 (DKK3) ELISA Kit
Human Dickkopf-Related Protein 3 (DKK3) ELISA Kit
This ELISA kit is designed to detect Human Dickkopf-Related Protein 3 (Human DKK3). The assay plate has been pre-coated with mouse anti-Human DKK3 monoclonal antibody. When the sample containing DKK3 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human DKK3 Antibody is added to the wells and binds to DKK3 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human DKK3 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE372
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
12.33 pg/mL
Detection Range
39.1-2500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Stem cells, Signal Transduction
Background
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Dickkopf-related protein 3
Regulatory Status
For Research Use Only
