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Human Galectin-3 (LGALS3) ELISA Kit

Human Galectin-3 (LGALS3) ELISA Kit

This ELISA kit is designed to detect Human Galectin-3 (Human LGALS3). The assay plate has been pre-coated with mouse anti-Human Galectin 3 monoclonal antibody. When the sample containing Galectin 3 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human Galectin 3 Antibody is added to the wells and binds to Galectin 3 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human Galectin 3 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.

Catalog No: BPE058
Regular price $624.00 USD
Regular price $480.00 USD Sale price $624.00 USD
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Product Details

Species Reactivity Human
Sensitivity 4.77 pg/mL
Detection Range 15.63-1000 pg/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 3.5 hour(s)
Research Areas Cell Biology, Neuroscience
Background LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life This product can be stored at 2-8C.
Analyte Galectin-3
Regulatory Status For Research Use Only
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