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Human HDAC8 (Histone Deacetylase 8) ELISA Kit
Human HDAC8 (Histone Deacetylase 8) ELISA Kit
The Human (HDAC8) Histone Deacetylase 8 ELISA Kit measures Histone Deacetylase 8 in samples. The plate has been pre-coated with Human HDAC8 antibody. HDAC8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human HDAC8 Antibody is added and binds to HDAC8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated HDAC8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human HDAC8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0988Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.055 ng/mL
Detection Range
0.1-35 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Histone Deacetylase 8
Regulatory Status
For Research Use Only
