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Human IL31RA (Interleukin-31 Receptor Subunit Alpha) ELISA Kit
Human IL31RA (Interleukin-31 Receptor Subunit Alpha) ELISA Kit
The Human (IL31RA) Interleukin-31 Receptor Subunit Alpha ELISA Kit measures Interleukin-31 Receptor Subunit Alpha in samples. The plate has been pre-coated with Human IL31RA antibody. IL31RA present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human IL31RA Antibody is added and binds to IL31RA in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated IL31RA antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human IL31RA. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5522Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
1.34 ng/L
Detection Range
3-900 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Immunology, Cytokines, Inflammation
Background
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed: 11877449, PubMed: 14504285, PubMed: 15627637, PubMed: 15194700). May function in skin immunity (PubMed: 15184896). Mediates IL31-induced itch, probably in a manner dependent on cation Channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Interleukin-31 Receptor Subunit Alpha
Regulatory Status
For Research Use Only
