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Human ING4 (Inhibitor of Growth Protein 4) ELISA Kit
Human ING4 (Inhibitor of Growth Protein 4) ELISA Kit
The Human (ING4) Inhibitor of Growth Protein 4 ELISA Kit measures Inhibitor of Growth Protein 4 in samples. The plate has been pre-coated with Human ING4 antibody. ING4 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human ING4 Antibody is added and binds to ING4 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ING4 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human ING4. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5465Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
9.82 ng/L
Detection Range
20-6000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cancer
Background
Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed: 16387653). Through chromatin acetylation it may function in DNA replication (PubMed: 16387653). May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed: 15251430, PubMed: 15528276). Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA (PubMed: 15029197). May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC (PubMed: 15029197). Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (PubMed: 15897452). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Inhibitor of Growth Protein 4
Regulatory Status
For Research Use Only
