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Human Interleukin-1 Receptor-Like 1 (IL-1RL1) ELISA Kit
Human Interleukin-1 Receptor-Like 1 (IL-1RL1) ELISA Kit
This ELISA kit is designed to detect Human Interleukin-1 Receptor-Like 1 (Human IL-1RL1). The assay plate has been pre-coated with mouse anti-Human ST2 monoclonal antibody. When the sample containing ST2 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human ST2 Antibody is added to the wells and binds to ST2 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human ST2 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE020
Regular price
$624.00 USD
Regular price
$480.00 USD
Sale price
$624.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
1.87 pg/mL
Detection Range
7.8-500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology, Cardiovascular
Background
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Interleukin-1 receptor-like 1
Regulatory Status
For Research Use Only
