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Human Junctional Adhesion Molecule A (F11R) ELISA Kit
Human Junctional Adhesion Molecule A (F11R) ELISA Kit
This ELISA kit is designed to detect Human Junctional Adhesion Molecule A (Human F11R). The assay plate has been pre-coated with mouse anti-Human JAM-A monoclonal antibody. When the sample containing JAM-A is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human JAM-A Antibody is added to the wells and binds to JAM-A in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human JAM-A present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE371
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
2.26 pg/mL
Detection Range
7.8-500 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cardiovascular, Signal Transduction
Background
Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Junctional adhesion molecule A
Regulatory Status
For Research Use Only
