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Human KCNJ3 (G Protein-activated Inward Rectifier Potassium Channel 1) ELISA Kit

Human KCNJ3 (G Protein-activated Inward Rectifier Potassium Channel 1) ELISA Kit

The Human (KCNJ3) G Protein-activated Inward Rectifier Potassium Channel 1 ELISA Kit measures G protein-activated inward rectifier potassium Channel 1 in samples. The plate has been pre-coated with Human KCNJ3 antibody. KCNJ3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human KCNJ3 Antibody is added and binds to KCNJ3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated KCNJ3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human KCNJ3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E1846Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 0.026 ng/mL
Detection Range 0.05-15 ng/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Background This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte G protein-activated inward rectifier potassium Channel 1
Regulatory Status For Research Use Only
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