1
/
of
1
Human KCNK18 (Potassium Channel Subfamily K Member 18) ELISA Kit
Human KCNK18 (Potassium Channel Subfamily K Member 18) ELISA Kit
The Human (KCNK18) Potassium Channel Subfamily K Member 18 ELISA Kit measures Potassium Channel subfamily K member 18 in samples. The plate has been pre-coated with Human KCNK18 antibody. KCNK18 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human KCNK18 Antibody is added and binds to KCNK18 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated KCNK18 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human KCNK18. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1789Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
0.019 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Outward rectifying potassium channel. Produces rapidly activating outward rectifier K+ currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Potassium Channel subfamily K member 18
Regulatory Status
For Research Use Only
