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Human KIF14 (Kinesin-like Protein Kif14) ELISA Kit
Human KIF14 (Kinesin-like Protein Kif14) ELISA Kit
The Human (KIF14) Kinesin-like Protein Kif14 ELISA Kit measures Kinesin-like protein KIF14 in samples. The plate has been pre-coated with Human KIF14 antibody. KIF14 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human KIF14 Antibody is added and binds to KIF14 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated KIF14 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human KIF14. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2776Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
4.58 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Tags and Cell Markers, Signal Transduction
Background
Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity).
Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480).
During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929).
Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087).
During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087).
During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity).
Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429).
Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Kinesin-like protein KIF14
Regulatory Status
For Research Use Only
