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Human KISS1 (Kisspeptin-1) ELISA Kit

Human KISS1 (Kisspeptin-1) ELISA Kit

The Human (KISS1) Kisspeptin-1 ELISA Kit measures Kisspeptin-1 in samples.

Catalog No: E3122Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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Packaging
2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 12.14 ng/L
Detection Range 20-1500 ng/L
Sample Type Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue
Incubation(s) 1.5 hour(s)
Research Areas Cell Biology, Neuroscience, Epigenetics and Nuclear Signaling, Cancer
Background Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Kisspeptin-1
Regulatory Status For Research Use Only
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