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Human LAG3 (Lymphocyte Activation Gene 3 Protein) ELISA Kit
Human LAG3 (Lymphocyte Activation Gene 3 Protein) ELISA Kit
The Human (LAG3) Lymphocyte Activation Gene 3 Protein ELISA Kit measures Lymphocyte activation gene 3 protein in samples. The plate has been pre-coated with Human LAG3 antibody. LAG3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human LAG3 Antibody is added and binds to LAG3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LAG3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human LAG3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E5606Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.025 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Immunology, Cancer
Background
Lymphocyte-activation gene 3, also known as LAG-3, is a protein which in humans is encoded by the LAG3 gene. LAG3, which was discovered in 1990 and was designated CD223 (cluster of differentiation 223) after the Seventh Human Leucocyte Differentiation Antigen Workshop in 2000, is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders. In soluble form it is also being developed as a cancer drug in its own right. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Lymphocyte activation gene 3 protein
Regulatory Status
For Research Use Only
