The Human (LAIR2) Leukocyte-associated Immunoglobulin-like Receptor 2 ELISA Kit measures Leukocyte-associated immunoglobulin-like receptor 2 in samples. The plate has been pre-coated with Human LAIR2 antibody. LAIR2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human LAIR2 Antibody is added and binds to LAIR2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated LAIR2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human LAIR2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
BackgroundLeukocyte-associated immunoglobulin-like receptor 2 is a protein that in humans is encoded by the LAIR2 gene. The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene. Source: UniProt Consortium (2025)
