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Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) ELISA Kit
Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) ELISA Kit
This ELISA kit is designed to detect Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (Human LAIR2). The assay plate has been pre-coated with mouse anti-Human LAIR2 monoclonal antibody. When the sample containing LAIR2 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Human LAIR2 Antibody is added to the wells and binds to LAIR2 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Human LAIR2 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE142
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Human
Sensitivity
1.19 pg/mL
Detection Range
5.47-350 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology
Background
Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD36, is a 131 amino acid protein containing one Ig-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Leukocyte-associated immunoglobulin-like receptor 2
Regulatory Status
For Research Use Only
