• Human (MAPILC3A) Microtubule-associated Proteins 1A/1B Light Chain 3A ELISA Kit
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Human MAPILC3A (Microtubule-associated Proteins 1A/1B Light Chain 3A) ELISA Kit

Human MAPILC3A (Microtubule-associated Proteins 1A/1B Light Chain 3A) ELISA Kit

The Human (MAPILC3A) Microtubule-associated Proteins 1A/1B Light Chain 3A ELISA Kit measures Microtubule-Associated Proteins 1A, 1B Light Chain 3A in samples. The plate has been pre-coated with Human MAP1LC3A antibody. MAP1LC3A present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human MAP1LC3A Antibody is added and binds to MAP1LC3A in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated MAP1LC3A antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human MAP1LC3A. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E6855Hu
$595.00 USD
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Product Details

Species Reactivity Human
Sensitivity 11.63 ng/L
Detection Range 20-6000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Signal Transduction
Background Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed: 20713600, PubMed: 24290141). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed: 20713600). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed: 31006538, PubMed: 31006537). Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Microtubule-Associated Proteins 1A, 1B Light Chain 3A
Regulatory Status For Research Use Only
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