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Human MCOLN2 (Mucolipin 2) ELISA Kit
Human MCOLN2 (Mucolipin 2) ELISA Kit
The Human (MCOLN2) Mucolipin 2 ELISA Kit measures Mucolipin 2 in samples. The plate has been pre-coated with Human MCOLN2 antibody. MCOLN2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human MCOLN2 Antibody is added and binds to MCOLN2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated MCOLN2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human MCOLN2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2918Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.018 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Nonselective cation Channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation Channel with inwardly rectifying activity (PubMed: 19940139, PubMed: 19885840). May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway (PubMed: 17662026). May play a role in immune processes. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells (By similarity). In the innate immune response, may play a role in the regulation of chemokine secretion and macrophage migration (By similarity). Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events (PubMed: 19885840). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Mucolipin 2
Regulatory Status
For Research Use Only
