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Human NCSTN (Nicastrin) ELISA Kit
Human NCSTN (Nicastrin) ELISA Kit
The Human (NCSTN) Nicastrin ELISA Kit measures Nicastrin in samples. The plate has been pre-coated with Human NCSTN antibody. NCSTN present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human NCSTN Antibody is added and binds to NCSTN in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NCSTN antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human NCSTN. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6925Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
7.28 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed: 10993067, PubMed: 12679784, PubMed: 25043039, PubMed: 26280335, PubMed: 30598546, PubMed: 30630874). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Nicastrin
Regulatory Status
For Research Use Only
