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Human NEUROD2 (Neurogenic Differentiation Factor 2) ELISA Kit
Human NEUROD2 (Neurogenic Differentiation Factor 2) ELISA Kit
The Human (NEUROD2) Neurogenic Differentiation Factor 2 ELISA Kit measures Neurogenic differentiation factor 2 in samples. The plate has been pre-coated with Human NEUROD2 antibody. NEUROD2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human NEUROD2 Antibody is added and binds to NEUROD2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NEUROD2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human NEUROD2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2921Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.021 ng/mL
Detection Range
0.05-15 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling, Neuroscience
Background
Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Neurogenic differentiation factor 2
Regulatory Status
For Research Use Only
