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Human NIN (Ninein/Gsk3B Interacting Protein) ELISA Kit
Human NIN (Ninein/Gsk3B Interacting Protein) ELISA Kit
The Human (NIN) Ninein/Gsk3B Interacting Protein ELISA Kit measures Ninein/Gsk3B Interacting Protein in samples.
Catalog No:
E3201Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.05 ng/mL
Detection Range
0.1-30 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cell Biology
Background
A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets (PubMed: 27484798, PubMed: 25920809, PubMed: 16981698). The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively (PubMed: 27484798, PubMed: 16981698). Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B (PubMed: 25920809). During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (PubMed: 19830702). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Ninein/Gsk3B Interacting Protein
Regulatory Status
For Research Use Only
