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Human NLRP2 (Nacht, Lrr and Pyd Domains-containing Pprotein 2) ELISA Kit

Human NLRP2 (Nacht, Lrr and Pyd Domains-containing Pprotein 2) ELISA Kit

The Human (NLRP2) Nacht, Lrr and Pyd Domains-containing Pprotein 2 ELISA Kit measures NACHT,LRR and PYD domains-containing protein 2 in samples. The plate has been pre-coated with Human NLRP2 antibody. NLRP2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human NLRP2 Antibody is added and binds to NLRP2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NLRP2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human NLRP2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E4050hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 5.12 ng/L
Detection Range 10-3000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Cell Biology
Background Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte NACHT,LRR and PYD domains-containing protein 2
Regulatory Status For Research Use Only
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