1
/
of
1
Human NOTCH3 (Neurogenic Locus Notch Homolog Protein 3) ELISA Kit
Human NOTCH3 (Neurogenic Locus Notch Homolog Protein 3) ELISA Kit
The Human (NOTCH3) Neurogenic Locus Notch Homolog Protein 3 ELISA Kit measures Neurogenic locus notch homolog protein 3 in samples. The plate has been pre-coated with Human NOTCH3 antibody. NOTCH3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human NOTCH3 Antibody is added and binds to NOTCH3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NOTCH3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human NOTCH3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E3263Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
Couldn't load pickup availability
Product Details
Species Reactivity
Human
Sensitivity
36.17 ng/L
Detection Range
70-15000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543).
Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Neurogenic locus notch homolog protein 3
Regulatory Status
For Research Use Only
