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Human NTN1 (Netrin-1) ELISA Kit
Human NTN1 (Netrin-1) ELISA Kit
The Human (NTN1) Netrin-1 ELISA Kit measures Netrin-1 in samples. The plate has been pre-coated with Human NTN1 antibody. NTN1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human NTN1 Antibody is added and binds to NTN1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated NTN1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human NTN1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1277Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.39 pg/mL
Detection Range
10-3000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Neuroscience
Background
Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed: 28483977). Involved in dorsal root ganglion axon projection towards the spinal cord (PubMed: 28483977). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis (PubMed: 15343335). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Netrin-1
Regulatory Status
For Research Use Only
