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Human PADI3 (Protein-arginine Deiminase Type-3) ELISA Kit
Human PADI3 (Protein-arginine Deiminase Type-3) ELISA Kit
The Human (PADI3) Protein-arginine Deiminase Type-3 ELISA Kit measures Protein-arginine deiminase type-3 in samples. The plate has been pre-coated with Human PADI3 antibody. PADI3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PADI3 Antibody is added and binds to PADI3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PADI3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PADI3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4252hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
5.09 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Peptidyl arginine deiminase, type III, also known as PADI3, is a protein which in humans is encoded by the PADI3 gene. This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Protein-arginine deiminase type-3
Regulatory Status
For Research Use Only
