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Human PAI-1 (Plasminogen Activator Inhibitor 1) ELISA Kit
Human PAI-1 (Plasminogen Activator Inhibitor 1) ELISA Kit
The Human (PAI-1) Plasminogen Activator Inhibitor 1 ELISA Kit measures Plasminogen Activator Inhibitor 1 in samples.
Catalog No:
E1159Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.019 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cell Biology
Background
Serine protease inhibitor. Inhibits TMPRSS7 (PubMed: 15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed: 8481516, PubMed: 9207454, PubMed: 17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed: 9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed: 15001579, PubMed: 9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed: 18386027). It is involved in cellular and replicative senescence (PubMed: 16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed: 25808697, PubMed: 27046084). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Plasminogen Activator Inhibitor 1
Regulatory Status
For Research Use Only
