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Human PGC1A (Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha) ELISA Kit
Human PGC1A (Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha) ELISA Kit
The Human (PGC1A) Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha ELISA Kit measures Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha in samples.
Catalog No:
E6831Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.109 ng/mL
Detection Range
0.2-60 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Metabolism
Background
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha
Regulatory Status
For Research Use Only
