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Human PLXNB2 (Plexin B2) ELISA Kit
Human PLXNB2 (Plexin B2) ELISA Kit
The Human (PLXNB2) Plexin B2 ELISA Kit measures Plexin B2 in samples. The plate has been pre-coated with Human PLXNB2 antibody. PLXNB2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PLXNB2 Antibody is added and binds to PLXNB2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PLXNB2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PLXNB2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2636Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
3.94 ng/L
Detection Range
7-1500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling (By similarity).
Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development (By similarity).
Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248' (By similarity).
Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development (By similarity).
Regulates the migration of cerebellar granule cells in the developing brain (By similarity).
Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12183458).
Plays a role in axon guidance, invasive growth and cell migration (PubMed:15184888).
May modulate the activity of RAC1 and CDC42 (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Plexin B2
Regulatory Status
For Research Use Only
