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Human PMPCB (Mitochondrial-processing Peptidase Subunit Beta) ELISA Kit

Human PMPCB (Mitochondrial-processing Peptidase Subunit Beta) ELISA Kit

The Human (PMPCB) Mitochondrial-processing Peptidase Subunit Beta ELISA Kit measures Mitochondrial-processing peptidase subunit beta in samples. The plate has been pre-coated with Human PMPCB antibody. PMPCB present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PMPCB Antibody is added and binds to PMPCB in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PMPCB antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PMPCB. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E5685Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 7.65 ng/L
Detection Range 15-3000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Background Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (PubMed:29576218) (Probable). Preferentially, cleaves after an arginine at position P2 (By similarity). Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (PubMed:22354088). Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Mitochondrial-processing peptidase subunit beta
Regulatory Status For Research Use Only
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