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Human PREX2 (Phosphatidylinositol 3,4, 5-Trisphosphate-dependent Rac Exchanger 2 Protein) ELISA Kit

Human PREX2 (Phosphatidylinositol 3,4, 5-Trisphosphate-dependent Rac Exchanger 2 Protein) ELISA Kit

The Human (PREX2) Phosphatidylinositol 3,4, 5-Trisphosphate-dependent Rac Exchanger 2 Protein ELISA Kit measures Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein in samples. The plate has been pre-coated with Human PREX2 antibody. PREX2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PREX2 Antibody is added and binds to PREX2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PREX2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PREX2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E7272Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 4.88 ng/L
Detection Range 10-2000 ng/L
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Signal Transduction
Background Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 2 Protein
Regulatory Status For Research Use Only
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