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Human PSMB6 (Proteasome Subunit Beta Type 6) ELISA Kit
Human PSMB6 (Proteasome Subunit Beta Type 6) ELISA Kit
The Human (PSMB6) Proteasome Subunit Beta Type 6 ELISA Kit measures Proteasome Subunit Beta Type 6 in samples. The plate has been pre-coated with Human PSMB6 antibody. PSMB6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PSMB6 Antibody is added and binds to PSMB6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PSMB6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PSMB6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2427Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
2.98 ng/L
Detection Range
7-1500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic Peptides (20S-PA28 complex). Within the 20S core complex, PSMB6 displays a peptidylglutamyl-hydrolizing activity also termed postacidic or caspase-like activity, meaning that the Peptides bond hydrolysis occurs directly after acidic residues. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Proteasome Subunit Beta Type 6
Regulatory Status
For Research Use Only
