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Human PTGES (Prostaglandin E Synthase) ELISA Kit
Human PTGES (Prostaglandin E Synthase) ELISA Kit
The Human (PTGES) Prostaglandin E Synthase ELISA Kit measures Prostaglandin E Synthase in samples. The plate has been pre-coated with Human PTGES antibody. PTGES present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human PTGES Antibody is added and binds to PTGES in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PTGES antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human PTGES. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E4229hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
7.57 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (PubMed: 18682561, PubMed: 10377395, PubMed: 12672824, PubMed: 12460774, PubMed: 10869354, PubMed: 12244105). Plays a key role in inflammation response, fever and pain (By similarity). Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2 (PubMed: 12244105, PubMed: 12672824). In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (PubMed: 12672824). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Prostaglandin E Synthase
Regulatory Status
For Research Use Only
