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Human RARB (Retinoic Acid Receptor Beta) ELISA Kit
Human RARB (Retinoic Acid Receptor Beta) ELISA Kit
The Human (RARB) Retinoic Acid Receptor Beta ELISA Kit measures Retinoic Acid Receptor Beta in samples. The plate has been pre-coated with Human RARB antibody. RARB present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human RARB Antibody is added and binds to RARB in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RARB antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human RARB. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E6086Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
2.16 ng/L
Detection Range
5-1000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed: 12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed: 29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Retinoic Acid Receptor Beta
Regulatory Status
For Research Use Only
