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Human RCN3 (Reticulocalbin 3) ELISA Kit
Human RCN3 (Reticulocalbin 3) ELISA Kit
The Human (RCN3) Reticulocalbin 3 ELISA Kit measures Reticulocalbin 3 in samples. The plate has been pre-coated with Human RCN3 antibody. RCN3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human RCN3 Antibody is added and binds to RCN3 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RCN3 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human RCN3. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2940Hu
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Human
Sensitivity
0.024 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed: 16433634, PubMed: 28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed: 28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed: 16433634). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Reticulocalbin 3
Regulatory Status
For Research Use Only
