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Human RPL13A (60S Ribosomal Protein L13A) ELISA Kit

Human RPL13A (60S Ribosomal Protein L13A) ELISA Kit

The Human (RPL13A) 60S Ribosomal Protein L13A ELISA Kit measures 60S Ribosomal Protein L13A in samples. The plate has been pre-coated with Human RPL13A antibody. RPL13A present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human RPL13A Antibody is added and binds to RPL13A in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RPL13A antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human RPL13A. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

Catalog No: E4883Hu
Regular price $595.00 USD
Regular price $458.00 USD Sale price $595.00 USD
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2.5 weeks
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Product Details

Species Reactivity Human
Sensitivity 0.019 ng/mL
Detection Range 0.05-20 ng/mL
Sample Type Serum, plasma, cell culture supernates
Incubation(s) 1.5 hour(s)
Research Areas Epigenetics and Nuclear Signaling
Background Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA. Source: UniProt Consortium (2025)
Shipping Condition Shipped on cold gel packs.
Storage Condition and Shelf Life 2-8C
Analyte 60S Ribosomal Protein L13A
Regulatory Status For Research Use Only
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